Description
TB-500 5mg from Evolve Peptides is 5mg of TB-500 in a sealed glass vial. TB-500 is a synthetic thymosin beta-4 peptide. It’s sold for laboratory research only.
What is TB-500?
Thymosin beta-4 is a 43-amino-acid protein found in nearly every cell, where it binds actin and helps control cell movement. TB-500 is the name used for synthetic thymosin beta-4 and for a short fragment of its active region.
It’s on the WADA prohibited list and isn’t an approved medicine.
How TB-500 acts in the lab
Thymosin beta-4’s main job is holding on to G-actin, the building block of the cell’s internal scaffolding. By controlling how much actin is free to polymerize, it controls how cells move and change shape.
Cell movement is the first step in repair, so that’s the link to the wound and blood vessel studies. The fragment often sold as TB-500 contains the actin-binding region, LKKTETQ.
TB-500 5mg product details
- Compound: TB-500
- Also known as: thymosin beta-4, Tβ4
- CAS number: 77591-33-4
- Molecular formula: C212H350N56O78S
- Molar mass: 4,963.4 g/mol
- Structure: 43 amino acids (thymosin beta-4)
- Amount: 5mg per vial
- Form: lyophilized (freeze-dried) powder
- SKU: EVP-TB500-5
- Use: laboratory research only
Published TB-500 studies
Goldstein and colleagues reviewed thymosin beta-4’s role in wound repair in 2012, covering faster closure of skin wounds and new blood vessel growth in animal models.
Bock-Marquette and colleagues reported in Nature (2004) that thymosin beta-4 improved heart cell survival after injury in mice.
For the original studies, try this PubMed search.
Reconstituting TB-500 5mg
Concentration is just the amount in the vial divided by the water you add. With 5mg in this vial:
- 1ml of bacteriostatic water gives 5mg/ml
- 2ml of bacteriostatic water gives 2.5mg/ml
- 3ml of bacteriostatic water gives 1.67mg/ml
Go with whichever number is easiest to work with in your protocol, and label the vial with the concentration and the date you mixed it.
Use sterile bacteriostatic water. Warm the sealed vial to room temperature first so no condensation gets in, add the water slowly along the glass wall, and swirl gently until it’s clear. Never shake.
How to store TB-500 5mg
The dry powder keeps best cold: 2 to 8°C in the fridge, or -20°C for long-term storage. After reconstitution, store it in the fridge and finish it within roughly four weeks.
TB-500 5mg lab reports and purity
The product photos for TB-500 5mg include:
- A certificate of analysis with identity, measured quantity and HPLC purity.
- An independent Janoshik Analytical test report. You can verify it on janoshik.com with the key printed at the bottom.
- An endotoxin report from a kinetic LAL assay.
Click any image to zoom in on the numbers. A few reports cover another TB-500 vial size made at the same time. Purity applies across sizes, while the quantity result is for the one the lab actually measured.
TB-500 sizes compared
- TB-500 5mg (this page): 5mg for $50.00, about $10.00 per mg
- TB-500 10mg: 10mg for $90.00, about $9.00 per mg
TB-500 5mg is the smallest option. It’s the one to start with for a pilot run or when you’re testing a new protocol.
Peptides often ordered with TB-500
- ARA-290 10mg, EPO-derived peptide
- BPC-157 10mg, 15-amino-acid peptide
- KPV 5mg, alpha-MSH tripeptide
- LL-37 5mg, antimicrobial peptide
- BPC-157 and TB-500 Blend 5mg/5mg, BPC-157 and TB-500 in one vial
Browse the full healing and recovery peptides range, or see every vial on our research peptides page.
Common questions about TB-500 5mg
How much is in the TB-500 5mg vial?
5mg of lyophilized powder. The amount is printed on the label.
What do I mix TB-500 5mg with?
Sterile bacteriostatic water. The reconstitution section above shows the concentration for each volume.
How should I store it?
Sealed vials go in the fridge, or the freezer for long-term storage. Once mixed, refrigerate and use within about 28 days.
Can TB-500 be used in people or animals?
No. It’s sold for laboratory research only and isn’t approved for human or veterinary use.
Is it in stock?
Yes, TB-500 5mg is in stock now.
Buy TB-500 5mg online
Order TB-500 5mg now for $50.00. It’s in stock, and checkout takes about two minutes. Add a vial of bacteriostatic water if you don’t have any, so you’re ready to reconstitute when it arrives.
Need more for the same project? See the rest of our healing and recovery peptides.
For laboratory research use only. Not for human or veterinary use. Not evaluated by the FDA.












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