MOTS-c 10mg

Description

Our MOTS-c 10mg vial holds 10mg of lyophilized MOTS-c, a mitochondrial-derived peptide. It’s for in-vitro and lab research only.

MOTS-c at a glance

MOTS-c is a 16-amino-acid peptide encoded in the mitochondrial 12S rRNA gene. It was described in 2015 by Pinchas Cohen’s group at USC.

It acts on metabolism, in part through AMPK.

How MOTS-c works

Most proteins are coded in the cell nucleus. MOTS-c is one of a handful of peptides coded in mitochondrial DNA instead. Its main target looks like the folate cycle, which feeds into AMPK activation and better glucose handling in muscle.

Under stress it can move into the nucleus and change gene expression. Circulating levels drop with age in both mice and people, which is why it’s studied in metabolism and aging.

MOTS-c 10mg product details

• Compound: MOTS-c
• CAS number: 1627580-64-6
• Molecular formula: C101H152N28O22S2
• Molar mass: 2,174.6 g/mol
• Sequence: Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg
• Amount: 10mg per vial
• Form: lyophilized (freeze-dried) powder
• SKU: EVP-MOTSC-10
• Use: laboratory research only

MOTS-c research

Lee and colleagues reported in Cell Metabolism (2015) that MOTS-c prevented diet-induced obesity and insulin resistance in mice.

Reynolds and colleagues showed in 2021 that it improved physical capacity in young, middle-aged and old mice.

To read the papers yourself, start with this PubMed search for MOTS-c.

Reconstituting MOTS-c 10mg

Here’s the math for 10mg of peptide:

• 1ml of bacteriostatic water gives 10mg/ml
• 2ml of bacteriostatic water gives 5mg/ml
• 3ml of bacteriostatic water gives 3.33mg/ml

Pick the volume that keeps your own calculations simple, then write the concentration and the mixing date on the label.

Most labs use bacteriostatic water. Let the vial reach room temperature, run the water slowly down the inside of the glass, then roll it gently until the powder dissolves. Don’t shake it. Shaking can shear peptide chains.

Storing MOTS-c 10mg

The dry powder keeps best cold: 2 to 8°C in the fridge, or -20°C for long-term storage. After reconstitution, store it in the fridge and finish it within roughly four weeks.

MOTS-c 10mg lab reports and purity

The product photos for MOTS-c 10mg include:

• A certificate of analysis with identity, measured quantity and HPLC purity.
• An endotoxin report from a kinetic LAL assay.

Click any image to zoom in on the numbers. Some of these reports were run on a different vial size of MOTS-c from the same production. The purity figure carries over; the quantity line refers to the vial that was tested.

Choosing a MOTS-c size

• MOTS-c 10mg (this page): 10mg for $60.00, about $6.00 per mg
• MOTS-c 40mg: 40mg for $179.90, about $4.50 per mg

MOTS-c 10mg is the smallest option. It’s the one to start with for a pilot run or when you’re testing a new protocol.

Peptides often ordered with MOTS-c

• NAD+ 1000mg, coenzyme
• L-Glutathione 600mg, antioxidant tripeptide
• SS-31 50mg, mitochondrial peptide
• Pinealon 10mg, bioregulator peptide
• Epithalon 5mg, tetrapeptide

Browse the full anti-aging peptides and weight loss peptides range, or see every vial on our research peptides page.

Common questions about MOTS-c 10mg

How much is in the MOTS-c 10mg vial?

10mg of lyophilized powder. The amount is printed on the label.

Is it in stock?

Yes, MOTS-c 10mg is in stock now.

Is MOTS-c 10mg lab tested?

Yes. The lab reports are in the product photos, so you can check purity before you order.

Which size should I buy?

Pick by how much you’ll use. Bigger vials cost less per milligram, smaller ones mean less sits open in the fridge. The size comparison above lists every MOTS-c option.

What do I mix MOTS-c 10mg with?

Sterile bacteriostatic water. The reconstitution section above shows the concentration for each volume.

Buy MOTS-c 10mg online

Order MOTS-c 10mg now for $60.00. It’s in stock, and checkout takes about two minutes. Add a vial of bacteriostatic water if you don’t have any, so you’re ready to reconstitute when it arrives.

Need more for the same project? See the rest of our anti-aging peptides and weight loss peptides.

For laboratory research use only. Not for human or veterinary use. Not evaluated by the FDA.