Description
Our Argireline 5mg vial holds 5mg of lyophilized Argireline, a cosmetic hexapeptide. It’s for in-vitro and lab research only.
About Argireline
Argireline (acetyl hexapeptide-8, or -3) is a synthetic peptide based on the N-terminal end of SNAP-25. It interferes with the SNARE complex that releases acetylcholine.
It’s used in topical anti-wrinkle products.
How Argireline acts in the lab
Muscles contract when nerve endings release acetylcholine, and that release depends on a protein complex called SNARE. SNAP-25 is one of its parts.
Argireline copies the end of SNAP-25 and competes with it, so fewer SNARE complexes form and less acetylcholine is released. That’s the basis for its use in expression-line studies.
Argireline 5mg specifications
- Compound: Argireline
- Also known as: acetyl hexapeptide-8
- CAS number: 616204-22-9
- Molecular formula: C34H60N14O12S
- Molar mass: 889.0 g/mol
- Sequence: Ac-Glu-Glu-Met-Gln-Arg-Arg-NH2
- Amount: 5mg per vial
- Form: lyophilized (freeze-dried) powder
- SKU: EVP-ARGI-5
- Use: laboratory research only
Argireline research
Blanes-Mira and colleagues reported in 2002 that topical argireline reduced wrinkle depth in a small study.
Its skin penetration is debated.
To read the papers yourself, start with this PubMed search for Argireline.
Argireline purity and lab testing
Scroll through the Argireline 5mg photos and you’ll find:
- A certificate of analysis with identity, measured quantity and HPLC purity.
- An endotoxin report from a kinetic LAL assay.
Click any image to zoom in on the numbers. Each report names the batch it covers, so match it against the batch number on your label.
How to reconstitute Argireline 5mg
Here’s the math for 5mg of peptide:
- 1ml of bacteriostatic water gives 5mg/ml
- 2ml of bacteriostatic water gives 2.5mg/ml
- 3ml of bacteriostatic water gives 1.67mg/ml
Pick the volume that keeps your own calculations simple, then write the concentration and the mixing date on the label.
Use sterile bacteriostatic water. Warm the sealed vial to room temperature first so no condensation gets in, add the water slowly along the glass wall, and swirl gently until it’s clear. Never shake.
Storing Argireline 5mg
Store sealed vials in the fridge (2 to 8°C) or freezer (-20°C), away from light. Mixed solution goes back in the fridge and should be used within about 28 days.
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Argireline 5mg questions
How much is in the Argireline 5mg vial?
5mg of lyophilized powder. The amount is printed on the label.
What do I mix Argireline 5mg with?
Sterile bacteriostatic water. The reconstitution section above shows the concentration for each volume.
How should I store it?
Sealed vials go in the fridge, or the freezer for long-term storage. Once mixed, refrigerate and use within about 28 days.
Can Argireline be used in people or animals?
No. It’s sold for laboratory research only and isn’t approved for human or veterinary use.
Is it in stock?
Yes, Argireline 5mg is in stock now.
Buy Argireline 5mg from Evolve Peptides
Order Argireline 5mg now for $30.00. It’s in stock, and checkout takes about two minutes. Add a vial of bacteriostatic water if you don’t have any, so you’re ready to reconstitute when it arrives.
Need more for the same project? See the rest of our skin peptides.
For laboratory research use only. Not for human or veterinary use. Not evaluated by the FDA.
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